It is testament to the diligence and scientific expertise of my colleagues at UKHSA, and the genomic sequencing capacity developed through the pandemic, that this new variant has been identified and analysed so quickly. The first genomes of this variant were uploaded to the international GISAID database on 22 November. "The symptoms of the Omicron variant, which includes the BA.2 lineage, and the Delta variant, are similar," says Dr. Erica Johnson, MD, the chair of the Infectious Disease Board of the . Delta and Omicron Cases are being eclipsed by BA2 Variant rapidly. As viruses mutate often and at random, it is not unusual for small numbers of cases to arise featuring new sets of mutations. All age groups are affected, including the 75s and over, who are due a spring booster jab to top up protection. According to the COVID Symptom Study, the five most common symptoms are the same: Runny nose, headache, fatigue, sneezing and sore throat. As we learn to live safely with COVID-19, there are actions we can all take to help reduce the risk of catching COVID-19 and passing it on to others. This matches a recent study led by Oxford University and the Office for National Statistics (ONS), using data from the COVID-19 Infection Survey produced by the latter. The UK Health Security Agency (UKHSA) has published a new variant technical briefing containing updated analysis on Omicron hospitalisation risk and vaccine efficacy against symptomatic disease and hospitalisation. Of these, XD and XF are recombinants of Delta and Omicron BA.1, while XE is a recombinant of Omicron BA.1 and BA.2. UKHSAwill continue to carry out laboratory and epidemiological investigations to better understand the characteristics of this variant. [92] Reactions [ edit] Vaccine producers [ edit] Take a vaccine to protect yourself against COVID-19. Can Nigeria's election result be overturned? Where individuals are identified as being a possible or probable case, their close contacts will be contacted and advised to isolate for 10 days and to take a test. While evidence is still emerging, so far it does not appear this variant causes more severe disease or renders the vaccines currently deployed any less effective. The new strain has several key mutations, with the most important of those occurring in the spike protein that studs the outside of the virus. BA.2 has been under close . This designation means that data relating to BA.2.75 will now be reported separately from other BA.2 cases. However, any stay in hospital for a child is too long if youre a parent and its important we all take precautions to avoid the spread of infection. Based on the reports from doctors treating the Covid variant and patients battling. But the preliminary assessment found no evidence that vaccines would be any less effective against symptomatic disease for either sub-variant. According to the World Health Organization (WHO), nearly 99% of viral DNA submitted to the global GISAID database as of 25 January were identified as this sub-variant. Health and Social Care Secretary Sajid Javid said: This data is yet more evidence that vaccines remain our best line of defence against COVID-19. UKHSA will continue to designate new variants, and these will receive a variant number (in the format V-date-number). UKHSA continues to monitor and study variants of SARS-CoV-2 closely and is working with academic partners to rapidly assess the significance of the lineages BA.4 and BA.5. "We must remain vigilant and take up vaccinations. But it is worth noting that Denmark has seen similar trends in terms of hospital admissions and intensive care as the UK has, suggesting BA.2 does not mark a sea-change in severity. Yet fears of another Omicron wave in the United States may be. One case is located in Camden, London, and one case is located in Wandsworth, London. There are differences in the populations that have received different vaccines. The UK Health Security Agency (UKHSA) has released variant technical briefing 41. There are indications of a small rise in children admitted to hospital, but these early signals need further investigations before we can draw any conclusions about whether Omicron causes more severe illness in children. It contains updated analysis on Omicron hospitalisation risk, vaccine efficacy against symptomatic disease from Omicron, and the COVID-19 reinfection rate. Neutralisation studies are currently being undertaken at the University of Oxford. Here is what we know about it. News stories, speeches, letters and notices, Reports, analysis and official statistics, Data, Freedom of Information releases and corporate reports. For some more vulnerable a third dose is available. Thanks to the expertise of scientists at UKHSA and partner organisations, were able to respond quickly to new variations of the virus. Runny nose. It appears to have a growth advantage compared to the version of Omicron, BA.1, that has swept the globe. ; BA.5 sometimes gives rise to more marked symptomssometimes with digestive symptoms . A detrimental change in biological properties (changes in transmissibility, severity or immune evasion) compared to the current dominant variant. The best way that you can protect yourself is to come forward for your first 2 doses of vaccine, or your booster jab and do everything you can to stop onward transmission of the infection. An important question is whether BA.2 or BA.3 will become a new dominating "variant of concern". Where individualsare suspected or confirmed to have theOmicron variantas the result of testing, their close contacts will be contacted by NHS Test and Trace, required to self-isolate and asked to take aPCRtest,regardless of whether they have been vaccinated. Please make sure you follow all the available guidance. We have now identified cases in the East Midlands, East of England, London and North West. Updated Jan. 27, 2023 The omicron subvariant of COVID-19, BA.5, became one of the dominant strains of the virus in the fall of 2022 in the U.S. At that time, it was the most easily spread strain to date and is able to evade immunity from COVID infection and vaccination. Vaccination is critical to help us bolster our defences against this new variant please get your first, second, third or booster jab without delay. However, it should serve as objective evidence that this pandemic is not over. Omicron continues to grow faster than Delta, with an increased risk of transmission, particularly in contacts outside of the household. The designation was made on the basis of increasing numbers of BA.2 sequences identified both domestically and internationally. As the coronavirus continues to evolve, a new highly contagious Omicron variant is appearing in India and other nations, including the United States, experts say.. . UKHSA has also published analyses related to the original Omicron strain BA.1. This particular recombinant, XE, has shown a variable growth rate and we cannot yet confirm whether it has a true growth advantage. UKHSA is gathering scientific information as quickly as possible in order to inform the right balance of interventions to prevent transmission and protect lives. Vaccination is critical to help us bolster our defences against this new variant please get your first, second, third or booster jab without delay. ROCHESTER, Minn. The World Health Organization designated COVID-19 variant B.1.1.529, named omicron, a "variant of concern" on Nov. 26, 2021, and the first confirmed case in the U.S. was on Dec. 1, 2021. And even if it does become the dominant version of Omicron, it may not actually alter the trajectory of the pandemic in countries that have seen a big wave of BA.1. This is still a very small number of cases but is being investigated carefully to understand whether it is related to travel, any other variant or whether there is evidence of spread of Omicron beginning in the community. BA.2 Omicron Subvariant Can Damage Your Lungs, Cause More Severe Disease Than You Can Expect: Study BA.2 Omicron Subvariant Can Damage Your Lungs, Cause More Severe Disease Than You Can. As of 20 October, there were 15,120 cases of VUI-21OCT-01 confirmed by whole genome sequences in England since it was first detected in July. Latest updates on SARS-CoV-2 variants detected in the UK. Please take up this offer as soon as you are invited to protect yourself, your families and your communities. Both have links to travel to Southern Africa. UKHSA analysis shows that the risk of hospital admission for an identified case with Omicron is reduced compared to a case of Delta. There is currently no evidence of community transmission within the UK. Hospital cases are also rising, but vaccines are still helping to stop many severe. As viruses mutate into new variants, they sometimes split or branch off into sub-lineages. Aside from all of the usual COVID symptoms, like a dry cough, a scratchy throat, fatigue, and muscle aches, the Stealth variant is thought to cause a few other distinct issues. BA.2 continues to demonstrate a substantial growth advantage. It contains epidemiological data and updated analysis of COVID-19 variants currently circulating in the UK. As of 17 May, 115 cases of BA.4 and 80 cases of BA.5 have been confirmed in England and the latest UKHSA variant technical briefing has been published today. In the most recent week of data (specimen dates from 30 November 2021 reported as of 6 December), the number of cases with SGTF has increased to 705. Dr Susan Hopkins, Chief Medical Advisor for UKHSA, said: Ongoing variant analysis is an important part of our pandemic response. UKHSA has updated its stay at home guidance and non-household contacts guidance to reflect changes to self-isolation requirements for contacts of people who have been identified as a suspected or confirmed case of the Omicron variant of COVID-19. We have started to see cases where there are no links to travel, suggesting that we have a small amount of community transmission. However, it remains too early to draw any definitive conclusions on hospital severity, and the increased transmissibility of Omicron and the rising cases in the over 60s population in England means it remains highly likely that there will be significant pressure on the NHS in coming weeks. This analysis found that the risk of presentation to emergency care or hospital admission with Omicron (testing for symptomatic or asymptomatic infection) was approximately half of that for Delta, while the risk of hospital admission alone with Omicron was approximately one-third of that for Delta. Health and Social Care Secretary, Sajid Javid, said: We are learning to live with this virus and thanks to our world-leading surveillance system we can rapidly detect and carefully monitor any genetic changes to COVID-19. As of 24 January 2022, 1,072 genomically confirmed cases of BA.2 have been identified in England and all assessments remain preliminary whilst case numbers are relatively low. Our continued genomic surveillance allows us to detect them and assess whether they are significant. This sub-lineage, which was designated by Pangolin on 6 December 2021, does not have the spike gene deletion at 69-70 that causes S-gene target failure (SGTF), which has previously been used as a proxy to detect cases of Omicron. When combined with VE against symptomatic disease, the reduced risk of hospitalisation climbed to 92% 2 to 4 weeks after a third dose of the vaccine, down to 83% after 10 weeks or more. One study has suggested that it may be difficult to identify this variant . This is consistent with analysis published yesterday by Imperial College London and the University of Edinburgh. This analysis excludes individuals with confirmed previous COVID-19 infection. In total, 40 countries have uploaded 8,040 BA.2 sequences to GISAID since 17 November 2021. Dr Jenny Harries, Chief Executive of UKHSA, said: We are continuing our efforts to understand the effect of this variant on transmissibility, severe disease, mortality, antibody response and vaccine efficacy. Working from home where possible, consistently wearing masks in crowded or enclosed spaces, washing your hands regularly and isolating and getting tested if you feel unwell are also vitally important in reducing the impact of COVID-19 this winter. Typical meningitis symptoms include neck stiffness or pain, numbness, tingling, and sensitivity to light. Working alongside Cambridge University MRC Biostatistics unit, UKHSA analysed 528,176 Omicron cases and 573,012 Delta cases between 22 November and 26 December to assess the risk of hospitalisation in England after testing positive for Omicron. Neither BQ.1 nor XBB have been designated as variants of concern and UKHSA is monitoring the situation closely, as always. The UK Health Security Agency (UKHSA) has identified 8 further cases of COVID-19 with mutations consistent with B.1.1.529 in England, in addition to the previous 5 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529. We will continue to closely analyse all available biological, epidemiological and genomic evidence for any SARS-CoV-2 variant in the UK or internationally. Following the first 2 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529 on 27 November, the UK Health Security Agency (UKHSA) has identified one further case of COVID-19 with mutations consistent with B.1.1.529 in the UK. Initial data suggests that LFDs are as likely to detect Omicron as other variants including Delta, which has been the dominant variant in the UK from May to December 2021. Taste Lost is one of the Omicron BA2 Symptoms. BA.2 Symptoms Not That Different From Omicron, Delta. Omicron has branched into three lineages, explains Thomas Russo, M.D., professor and chief of infectious disease at the University at Buffalo in New York: BA.1, BA.2, and BA.3. Please take up this offer as soon as you are eligible to protect yourself, your families and your communities. As I previously reported, omicron subvariants have a shorter incubation period, which is why the symptoms may appear earlier. The latest data confirmed that among those who had received 2 doses of AstraZeneca, there was no effect against Omicron from 20 weeks after the second dose. According to Boden-Albala said, those symptoms may include the following: Fever Chills Fatigue Cough Body aches Shortness of breath Sore throat Additionally, some people may report upper. However, some experts believe that BA.2 doesn't present symptoms different from the original Omicron. This includes analysing live samples of the new variant in our laboratories to investigate properties such as response to current vaccines. Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, National flu and COVID-19 surveillance report, higher risk of becoming seriously ill from respiratory infections, including COVID-19, this data should be interpreted with caution, This assessment is based on analysis of UK data, data on Omicron cases is published regularly here, Six cases of the SARS-CoV-2 variant known as B.1.1.529, Investigation of SARS-CoV-2 variants of concern: variant risk assessments, Investigation of SARS-CoV-2 variants: technical briefings, Coronavirus (COVID-19): guidance for local government, let fresh air in if meeting others indoors, wear a face covering or a face mask, particularly if you are in crowded and enclosed spaces. Of these, 20 were in England, 3 in Scotland and 1 in Wales. However, a small change may be enough to cause a difference in the virus properties in some circumstances. With the original version of the omicron variant, which swept across the U.S. at a dizzying speed last winter, the loss of taste and smell was not as common as with the earlier alpha and delta variants. Previous variants of concern which no longer meet the criteria will be redesignated. A recombinant variant occurs when an individual becomes infected with 2 or more variants at the same time, resulting in a mixing of their genetic material within the patients body. Headache. The UK Health Security Agency (UKHSA) has published a new variant technical briefing containing an updated Omicron risk assessment, alongside analysis on vaccine efficacy, sub-lineages and symptoms. Francois Balloux, Professor of Computational Systems Biology and director of the UCL Genetics Institute, said that BA.1 and BA.2 "can be considered as two epidemiologically largely equivalent sub-lineages of Omicron". According to Baric, Omicron is the first SARS-CoV-2 variant to evolve in the context of mounting immunity in the populationthe result of vaccines and prior infection with other forms of the . Those mutations are shared with the original omicron, but BA.2 also has . A thirddose was associated with a 68% (95% confidence interval 52 to 82%) reduced risk of hospitalisation when compared to similar unvaccinated individuals. There will be no other categorisation of variants, including no variant under investigation (VUI) category. The COVID Omicron sub-variant BA.2, informally dubbed the "Stealth Omicron" variant, is able to reinfect people who have already had Omicron, a new study suggests. People infected with Omicron are also less likely to experience fever or loss of taste and smell. This is more promising data which reinforces just how important vaccines are. While growth rates can be overestimated in early analyses of a new variant, the apparent growth advantage is currently substantial. Studies have already shown that this virus travels to different parts of the body, therefore gut-related issues are. The analysis looked at 581 people with confirmed Omicron. But at that point the sub-variant still appeared to account for less than one in 20 cases. In a lot of ways, it's a bad cold, a lot of respiratory symptoms, stuffy nose, coughing, body aches and fatigue," said Dr. Dennis Cunningham, the system medical director of infection control and. Omicron soon began branching off into a number of subvariants: BA.2 took off in the spring, and BA.5 came to dominate towards the end of the summer. The BBC is not responsible for the content of external sites. So, like the original omicron strain (BA.1), the primary symptoms of a mild BA.2 infection are a cough, fever, fatigue and possible loss of taste or smell. There is further data showing that effectiveness against symptomatic disease is significantly lower compared to the Delta variant, and wanes more quickly. AstraZeneca was the main vaccine used early in the programme in care homes and among those in clinical risk groups. Until we have this evidence, we must exercise the highest level of caution in drawing conclusions about any significant risks to peoples health. Studies have also shown that Omicron infects and multiplies in the upper airways 70 times faster than the previous Delta variant. The UKHSAs COVID-19 variant technical briefing 43, published today, includes epidemiological analysis that shows that Omicron BA.4 and BA.5 now make up more than half of new COVID-19 cases in England, accounting for approximately 22% and 39% of cases, respectively. UKHSA has also released a variant risk assessment for Omicron BA.4 and BA.5, summarising the emerging epidemiology and laboratory evidence. BA.3 shares most of its mutations with BA.1 and BA.2 except for one. Early data shows that young children who are hospitalised experience mild illness and are discharged after short stays in hospital. UKHSAreleases weekly updates on the number of confirmed new cases of variants of concern and variants under investigation identified in the UK. The Omicron BA.2 subvariant is fast becoming the dominant strain of COVID-19, with symptoms similar to previous strains of the virus. The symptoms of omicron BA.2.75 are mostly flu-like and may last more than 4-5 days. You have rejected additional cookies. The individuals that have tested positive are not connected to each other and are not linked to the previously confirmed cases. Once again, we urge everyone who is able to get a booster jab to come forward and do so. As of 2 May 2022, 21 confirmed cases of Omicron BA.4 and 19 confirmed cases of Omicron BA.5 have been detected in England. As is routine for any new variants under investigation,UKHSAis carrying out laboratory and epidemiological investigations to better understand the characteristics of this variant. Dr Mary Ramsay, Head of Immunisation at UKHSA, said: These early estimates should be treated with caution but they indicate that a few months after the second jab, there is a greater risk of catching the Omicron variant compared to Delta strain. Everyone should complete a primary course as soon as possible for most this will be a first and second dose. Read about our approach to external linking. This analysis is preliminary and highly uncertain because of the small numbers of Omicron cases currently in hospital, inability to effectively measure all previous infections and the limited spread of Omicron into older age groups. None of the cases to date is known to have been hospitalised or died. There will be a coprimary endpoint : Neutralizing antibody titers against the SARS-CoV-2 variant of most prominent public health interest according to pandemic evolution (among D614G, B.1.351, Omicron sub-variants BA.4-5, BQ1.1 and XBB or another recent variant) and against one of the variant targeted by the vaccines. The World Health Organization has been monitoring SARS-CoV-2 (the virus that causes Covid-19) since January 2020, during which time the variant Omicron has been identified, which is technically known as BA.1 or B.1.1.529.The WHO is now monitoring a sub-variant of Omicron, known as BA.2, which has been described as "stealth Omicron," because it has genetic mutations that potentially make it . SGTF is not a 100% accurate test for Omicron and results are regularly evaluated against sequencing to ensure they are interpreted correctly. Night sweats Scratchy throat Dry cough Mild muscle aches In data published by the UKHSA on January 14, they found that NHS test and trace data revealed a loss of smell or taste was reported less. Consider wearing a face covering when in crowded places. We are working as fast as possible to gather more evidence about any impact the new variant may have on severity of disease or vaccine effectiveness. Our data shows that getting the booster vaccine is more effective against this variant than 2 doses alone. To help us improve GOV.UK, wed like to know more about your visit today. The team at ZOE, a study that tracks symptoms . More recent data on Omicron cases is published regularly here. Because of a quirk in how it shows up in test results, we can see the numbers of suspected BA.2 doubled in the week up to 24 January. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. Dr Jenny Harries, Chief Executive of the UK Health Security Agency, said: Viruses mutate often and at random, and it is not unexpected that new variants will continue to arise as the pandemic goes on, particularly while the case rate remains high. However, UKHSA scientists say there is no room to be complacent. What's the least amount of exercise we can get away with? Susan Hopkins, Chief Medical Adviser at UKHSA, said: The latest set of analysis is in keeping with the encouraging signs we have already seen. The total number of confirmed cases in England is now 13. Prior infection is 44% effective at preventing future infection, increasing to 71% with 3 doses of the vaccine.

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